286 research outputs found

    Fleur de Sel

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    Fleur de Sel (Summer)

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    Fleur de Sel (Alternate)

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    Remote Photonic THz Generation Using an Optical Frequency Comb and Multicore Fiber

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    [EN] This paper proposes and demonstrates a photonic THz generation technique based on an optical frequency comb and multicore fiber (MCF) transmission, with the advantage of remote generation with great reconfigurability and reduced digital signal processing (DSP). The feasibility of the proposed technique is evaluated experimentally comparing the performance when transmitting a data wavelength and a local oscillator for optical heterodyning over a single core or over different cores in a 1-km MCF link. The proposed remote photonic THz generation technique is demonstrated employing a 16QAM 12.5 GBd signal. A short wireless transmission at 183 GHz center frequency with 0.25 m antenna-separation is achieved after 1 km MCF, meeting the soft-decision decision forward error correction (SD-FEC) bit error rate (BER) recommendation of 2 center dot 10(-2). The analysis includes the received photocurrent range for which the BER meets the standard hard-decision forward error correction (HD-FEC) recommendation of 3.8 center dot 10(-3) BER. The BER performance is analyzed considering different DSP configurations, with and without frequency offset estimation (FOE) and decision-driven least mean squares (DD LMS) equalization. The performance of the remote photonic THz generation technique is evaluated comparatively against traditional free-running laser transmission over MCF, confirming the advantage of using comb generation to reduce the frequency offset fluctuation and simplify the DSP.This work was supported by Spanish State Research Agency under Grants PID2019-106163RJ-I00/AEI/10.13039/501100011033 MULTICORE+ and MINECO/FEDER UE RTI2018-101296-B-I00 MULTI-BEAM5G projects, in part by the European Union'sHorizon 2020 Research and Innovation Programme underGrant H2020-EU.2.1.1.-762119 ULTRAWAVE, and in part by the Engineering and Physical Sciences Research Council under Grant EPSRC EP/P003990/1 COALESCE. The work of Maria Morant supported by Generalitat Valenciana under Grant BEST/2019/047.Morant, M.; González-Guerrero, L.; Renaud, CC.; Llorente, R. (2021). Remote Photonic THz Generation Using an Optical Frequency Comb and Multicore Fiber. Journal of Lightwave Technology. 39(24):7621-7627. https://doi.org/10.1109/JLT.2021.311508476217627392

    Building an end user focused THz based ultra high bandwidth wireless access network: The TERAPOD approach

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    The TERAPOD project aims to investigate and demonstrate the feasibility of ultra high bandwidth wireless access networks operating in the Terahertz (THz) band. The proposed TERAPOD THz communication system will be developed, driven by end user usage scenario requirements and will be demonstrated within a first adopter operational setting of a Data Centre. In this article, we define the full communications stack approach that will be taken in TERAPOD, highlighting the specific challenges and aimed innovations that are targeted

    Cdk2 is critical for proliferation and self-renewal of neural progenitor cells in the adult subventricular zone

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    We investigated the function of cyclin-dependent kinase 2 (Cdk2) in neural progenitor cells during postnatal development. Chondroitin sulfate proteoglycan (NG2)–expressing progenitor cells of the subventricular zone (SVZ) show no significant difference in density and proliferation between Cdk2−/− and wild-type mice at perinatal ages and are reduced only in adult Cdk2−/− mice. Adult Cdk2−/− SVZ cells in culture display decreased self-renewal capacity and enhanced differentiation. Compensatory mechanisms in perinatal Cdk2−/− SVZ cells, which persist until postnatal day 15, involve increased Cdk4 expression that results in retinoblastoma protein inactivation. A subsequent decline in Cdk4 activity to wild-type levels in postnatal day 28 Cdk2−/− cells coincides with lower NG2+ proliferation and self-renewal capacity similar to adult levels. Cdk4 silencing in perinatal Cdk2−/− SVZ cells abolishes Cdk4 up-regulation and reduces cell proliferation and self- renewal to adult levels. Conversely, Cdk4 overexpression in adult SVZ cells restores proliferative capacity to wild-type levels. Thus, although Cdk2 is functionally redundant in perinatal SVZ, it is important for adult progenitor cell proliferation and self-renewal through age-dependent regulation of Cdk4
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